![[RDF data]](http://data.linkedct.org/snorql/rdf_flyer.24.gif)
Trial NCT00730509
Resource URI: http://data.linkedct.org/resource/trials/NCT00730509
| Property | Value |
|---|---|
| linkedct:brief_title | Effects of 5-Methyltetrahydrofolate and Vitamin B12 Supplemetation on Red Cell Membrane in Children With Cystic Fibrosis |
| linkedct:condition | <http://data.linkedct.org/resource/condition/3524> |
| linkedct:criteria | Inclusion Criteria: - cystic fibrosis Exclusion Criteria: - diabetes - chronic infections of the airways - regular antibiotics intake |
| linkedct:description | Cystic fibrosis (CF) is one of the most common fatal autosomal recessive disorders in the Caucasian population caused by mutations of gene for the cystic fibrosis transmembrane conductance regulator (CFTR). New experimental therapeutic strategies for CF propose a diet supplementation to affect the plasma membrane fluidity and to modulate the cellular amplified inflammatory response in CF target organs. Red blood cells (RBCs) were used to investigate plasma membrane, because RBCs share lipid, protein composition and organization with other cell types. |
| linkedct:download_date | Information obtained from ClinicalTrials.gov on December 30, 2009 |
| linkedct:eligibility_gender | Both |
| linkedct:eligibility_healthy_volunteers | Accepts Healthy Volunteers |
| linkedct:eligibility_maximum_age | 8 Years |
| linkedct:eligibility_minimum_age | 3 Years |
| linkedct:end_date | March 2006 |
| linkedct:enrollment | 31 (xsd:int) |
| linkedct:firstreceived_date | August 4, 2008 |
| linkedct:has_dmc | No |
| linkedct:id | NCT00730509 |
| linkedct:intervention | <http://data.linkedct.org/resource/intervention/57319> |
| rdfs:label | Trial NCT00730509 |
| linkedct:lastchanged_date | August 4, 2008 |
| linkedct:lead_sponsor_agency | <http://data.linkedct.org/resource/agency/2845> |
| linkedct:location | <http://data.linkedct.org/resource/location/80192> |
| linkedct:nct_id | NCT00730509 |
| linkedct:number_of_arms | 1 (xsd:int) |
| linkedct:number_of_groups | 0 (xsd:int) |
| linkedct:official_title | Preliminary Evidences of Active Form of Folic Acid and Vitamin B12 Supplementation to Ameliorate Cell Membrane in Children With Cystic Fibrosis |
| linkedct:org_study_id | UNIVR_REUM_01 |
| linkedct:overall_official | <http://data.linkedct.org/resource/overall_official/35529> |
| linkedct:overall_status | Completed |
| linkedct:oversight | <http://data.linkedct.org/resource/oversight/1550> |
| foaf:page | <http://clinicaltrials.gov/show/NCT00730509> |
| linkedct:phase | N/A |
| linkedct:primary_outcomes | <http://data.linkedct.org/resource/primary_outcomes/48041> |
| linkedct:reference | <http://data.linkedct.org/resource/reference/30230> |
| linkedct:secondary_outcomes | <http://data.linkedct.org/resource/secondary_outcomes/132751> |
| linkedct:source | Universita di Verona |
| linkedct:start_date | April 2004 |
| linkedct:study_design | Other, Open Label, Uncontrolled, Single Group Assignment |
| linkedct:study_type | Interventional |
| linkedct:summary | The purpose of this study is to determine whether 5 - methyltetrahydrofolate and vitamin B12 supplementation can ameliorate cell plasma membrane features in pediatric patients with cystic fibrosis |
| rdf:type | linkedct:trials |
| linkedct:verification_date | May 2008 |
